diff --git a/.changeset/add-hdbscan-python-3-12-10.md b/.changeset/add-hdbscan-python-3-12-10.md
new file mode 100644
index 0000000..33af6ec
--- /dev/null
+++ b/.changeset/add-hdbscan-python-3-12-10.md
@@ -0,0 +1,5 @@
+---
+"@platforma-open/milaboratories.runenv-python-3.12.10": patch
+---
+
+Add `hdbscan==0.8.44` (scikit-learn-contrib HDBSCAN) to the Python 3.12.10 runenv. Built from prebuilt wheels on linux-x64, macOS (universal2) and win-x64; compiled from the Cython sources on the native runner for linux-aarch64 (no ARM64 wheel on PyPI). Provides density-based clustering with out-of-sample assignment (`approximate_predict`), enabling the embedding-clustering block's large-dataset path.
diff --git a/python-3.12.10/config.json b/python-3.12.10/config.json
index df27c1d..705ab34 100644
--- a/python-3.12.10/config.json
+++ b/python-3.12.10/config.json
@@ -12,6 +12,7 @@
       "parasail==1.3.4",
       "numpy==2.2.6",
       "umap-learn==0.5.7",
+      "hdbscan==0.8.44",
       "PyYAML==6.0.3",
       "cudf-cu12==25.6.0",
       "scanpy==1.10.1",
@@ -71,6 +72,12 @@
           "reason": "No cp312 / Windows wheel; compile with MSVC. The shared runner workflow activates vcvars via milaboratory/github-ci/actions/setup-msvc-dev-cmd@v4 before this step runs, so the env (INCLUDE / LIB / LIBPATH / PATH plus DISTUTILS_USE_SDK) is in scope when pip wheel invokes setuptools.",
           "buildRequires": ["setuptools", "wheel"]
         }
+      },
+      "hdbscan": {
+        "linux-aarch64": {
+          "reason": "No cp312 / Linux ARM64 wheel on PyPI for hdbscan 0.8.44 (wheels exist for linux-x64, macOS universal2, and win-x64); compile the Cython sources on the native ARM runner.",
+          "buildRequires": ["setuptools", "wheel", "Cython", "numpy"]
+        }
       }
     }
   }